Preheat oven to 375 degrees.
I like to work with my biscuits when they are room temperature. Separate biscuits. Carefully stretch biscuits into 4" x 5" rectangles. Don't tear them. Set them on a greased, or parchment lined baking sheet.
Beat cream cheese, pumpkin puree, powdered sugar, 1 tsp. pumpkin pie spice, salt, and vanilla until it is smooth.
Spoon cream cheese mixture on short end of biscuits.
Pull corners of biscuit over cream cheese mixture to tuck cream cheese mixture in. Roll pastry up. Pinch seam to seal. Place seem side down.
Mix pumpkin pie spice and sugar together to make pumpkin spice sugar.
Brush pasties with evaporated milk. Sprinkle with pumpkin spice sugar.
Bake 10-12 minutes.
Serve warm. Pastries can be microwaved if you are serving them later.